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A Brief Overview on Chemistry and Biology of Benzoxepine

[ Vol. 14 , Issue. 9 ]

Author(s):

Naveen Kuntala, Jhonsee R. Telu, Jaya S. Anireddy and Sarbani Pal   Pages 1086 - 1098 ( 13 )

Abstract:


Background: The present review article is related to the synthesis and medicinal importance of benzoxepine and its derivatives. The study of heterocycles is an evergreen field in the branch of organic / medicinal chemistry and always attracts the attention of chemists working not only in the area of organic synthesis but also in natural products.

Methodology: The derivatives of benzoxepine exhibit a wide range of pharmacological properties such as antibacterial, anticancer, antioxidants, anti-inflammatory, anti-diabetic, antiviral, antiproliferative, antituberculosis, antispermetogenic and antipsychotic activities. Consequently, their syntheses have attracted significant interest. Various methodologies have been developed for the synthesis and functionalization of this class of compounds.

Conclusion: In the present article, the relevant and recent advances in the field will be briefly covered.

Keywords:

Benzoxepine, heterocycles, synthesis, medicinal importance, chemistry, biology.

Affiliation:

Centre for Chemical Sciences and Technology, Institute of Science and Technology, Jawaharlal Nehru Technological University Hyderabad, Kukatpally, Hyderabad-500085, Centre for Chemical Sciences and Technology, Institute of Science and Technology, Jawaharlal Nehru Technological University Hyderabad, Kukatpally, Hyderabad-500085, Centre for Chemical Sciences and Technology, Institute of Science and Technology, Jawaharlal Nehru Technological University Hyderabad, Kukatpally, Hyderabad-500085, Department of Chemistry, MNR Degree & PG College, Kukatpally, Hyderabad-500072

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