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Synthesis, Nematicidal Activity and Docking Study of Novel Pyrazole-4-Carboxamide Derivatives Against Meloidogyne incognita

[ Vol. 16 , Issue. 1 ]

Author(s):

Long Cheng, Wen Zhao, Zhong-Hua Shen, Tian-Ming Xu, Hong-Ke Wu, Wei-Li Peng* and Xing-Hai Liu*   Pages 29 - 35 ( 7 )

Abstract:


Background: A series of novel 2,6-dichloro-4-(trifluoromethyl)phenyl)-3-(difluoromethyl)- 1H-pyrazole-4-carboxamide derivatives were designed and synthesized.

Methods: All the title compounds were confirmed by 1H NMR and MS.

Results and Conclusion: The primarily nematicidal activity results indicated that some of them exhibited moderate control efficacy against the tomato root-knot nematode disease caused by Meloidogyne incognita.

Keywords:

Difluoromethylpyrazole, alkyl chain, nematicidal activity, synthesis, docking, Meloidogyne incognita.

Affiliation:

College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, Zhejiang Base of National Southern Pesticide Research Centre, Zhejiang Research Institute of Chemical Industry, Hangzhou 310023, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, Zhejiang Base of National Southern Pesticide Research Centre, Zhejiang Research Institute of Chemical Industry, Hangzhou 310023, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014

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